Therapeutic Penetrating Keratoplasty
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Therapeutic Penetrating Keratoplasty Surgery In Patiala
Therapeutic Penetrating Keratoplasty Explained
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Types of Therapeutic Keratoplasty
- Full-Thickness Therapeutic Keratoplasty: This involves replacing the entire thickness of the cornea with a donor cornea. It is used to treat serious infections or damage that affects the whole cornea.
- Tectonic Keratoplasty: This type focuses on repairing the structural integrity of the cornea, especially if there are large perforations or severe thinning. It helps to restore the cornea’s shape and function.
- Patch Graft: A smaller piece of donor cornea is used to cover a damaged area. It is a less extensive procedure compared to full-thickness keratoplasty and is often used for specific areas of damage or infection.
- Therapeutic Deep Anterior Lamellar Keratoplasty (DALK): Instead of replacing the entire cornea, this method removes and replaces only the front layers of the cornea. It is used for conditions affecting just the outer layers, leaving the deeper layers intact.
What is the role of preoperative antimicrobial therapy in TPK?
It reduces the risk of infection before the surgery.
What follow-up care is required after TPK?
Patients need regular check-ups to monitor healing and prevent complications.
What are the complications of DMEK surgery?
Can TPK restore vision?
Yes, TPK aims to restore vision by replacing the damaged cornea.
What are the benefits of using the latest technology in TPK?
Advanced technology improves precision, reduces risks, and speeds up recovery.
What is the success rate of TPK?
Success rates are high, but vary depending on the condition being treated.
How is the donor cornea prepared for TPK?
The donor cornea is carefully matched in size and shape to fit the recipient’s eye.
What is the recovery time for TPK?
Recovery can take several weeks to months, with regular follow-up visits.
Are there risks with TPK?
Risks include infection, graft rejection, and complications from surgery.
How long does TPK surgery take?
The procedure usually lasts a few hours, depending on the complexity.
How does TPK differ from other keratoplasties?
TPK replaces the entire cornea, while other types may only replace certain layers.

Dr. Vikas Mittal
Performed 2500+ DMEK Surgeries
20+ Years Experience

Dr. Amanjot Kaur Sandhu
Performed 800+ DMEK Surgeries
10+ Years Experience
Indications
Fungal Keratitis
Not improving (refractory) after maximal medical therapy;
Corneal perforation
Scleral involvement
Rapid corneal melt
Descemetocele
Bacterial Keratitis
Descemetocele
Corneal perforation
Limbus to limbus corneal involvement
Corneoscleral abscess
Non-compliance to medications
Resistant to conventional therapy
Pythium Keratitis
Descemetocele
Corneal perforation
Early limbal spread
Peripheral guttering
Corneal melt
Resistant to conventional therapy
Acanthamoeba Keratitis
Descemetocele
Corneal perforation
Severe scleral involvement
Non-resolving keratitis with maximal medical therapy
Viral Keratitis
Herpes simplex keratitis
Herpes zoster keratitis
Secondary bacterial infiltrate with corneal melt
Corneal perforation
Available Therapeutic Penetrating Keratoplasty Treatments at LJEI in Patiala
Therapeutic Penetrating Keratoplasty Surgeries
Therapeutic Penetrating Keratoplasty Surgeries
We feel proud to say that our doctors train various Cornea techniques to National and International doctors.
Most Advanced Eye Transplant Techniques Available
At LJ Eye Institute – Patiala we use most advanced Eye Transplant techniques whichever is available in the world, which further help to increase the success rate. Where using traditional techniques the success rate is 70% to 75%, the new techniques increase the success rate to 90% to 95%.These advanced techniques includes DMEK, DALK, DSEK, using such techniques we need not to change whole Cornea and we change only One or required number of layers of Cornea.

Technology @ LJEI
Technology Available For Therapeutic Penetrating Keratoplasty Treatments at LJEI in Patiala
Technology Available for Therapeutic Penetrating Keratoplasty at LJ Eye Institute – Patiala
At LJ Eye Institute – Patiala, we utilize the latest technology to ensure effective and precise therapeutic penetrating keratoplasty (TPK). Our advanced tools and techniques include:
- Femtosecond Laser: This laser provides highly accurate cuts, allowing us to precisely remove the damaged cornea and prepare the donor tissue. It enhances the accuracy of the procedure and improves healing.
- Optical Coherence Tomography (OCT): OCT gives detailed, cross-sectional images of the cornea, helping us assess its condition and plan the surgery. It aids in monitoring the cornea before, during, and after the procedure.
- Specular Microscopy: This tool measures the health and density of the corneal endothelial cells, essential for evaluating the need for TPK and checking the success of the transplant.
- Corneal Topography: This technology maps the surface of the cornea to provide information about its shape and thickness. It helps customize the TPK procedure to each patient’s specific needs.
- Digital Imaging Systems: These systems provide high-resolution images for precise surgical planning and monitoring of the graft integration and healing process.
By incorporating these advanced technologies, LJ Eye Institute – Patiala ensures that therapeutic penetrating keratoplasty is performed with the highest level of precision and care, leading to better outcomes and faster recovery for our patients.

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